Relationship between Toll-Like Receptor 8 Gene Polymorphisms and Pediatric Pulmonary Tuberculosis
نویسندگان
چکیده
منابع مشابه
Relationship between Toll-Like Receptor 8 Gene Polymorphisms and Pediatric Pulmonary Tuberculosis
OBJECTIVES Genetic variants in Toll-like receptors (TLRs) are considered a potential indicator for host susceptibility to and outcome of several infectious diseases including tuberculosis. The aim of this study was to determine whether -129 C/G and Met1Val polymorphisms of TLR8 were associated with pediatric pulmonary tuberculosis in Turkish population. METHODS The -129 C/G and Met1Val polymo...
متن کاملSilymarin inhibits Toll-like receptor 8 gene expression and apoptosis in Ramos cancer cell line
Objective: Silymarin is a herbal extract containing flavonolignans, and it has inhibitory effects against the growth of different cancer cell lines by inducing apoptosis. Toll-like receptors are suggested as a novel and attractive target to treat cancer. The current study aimed at examining the mechanism of silymarin-induced apoptosis in Ramos cells and investigating its effect...
متن کاملlack of association between toll like receptor-2 and toll like receptor-4 gene polymorphisms and other feature in iranian asthmatics patients.
asthma as a chronic inflammatory airway disease is considered to be the most common chronic disease that is involving genetic and environmental factors. toll like receptors (tlrs) and other inflammatory mediators are important in modulation of inflammation. in this study, we evaluated the role of tlr2 arg753gln and tlr4 asp299gly polymorphisms in the asthma susceptibility, progress, control lev...
متن کاملLack of association between toll like receptor-2 & toll like receptor-4 gene polymorphisms and Iranian asthmatics risk or features
© 2014 Pourfathollah et al; licensee Herbert Publications Ltd. This is an Open Access article distributed under the terms of Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0). This permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction Asthma is a complex and chronic disease in which alle...
متن کاملassociation between tlr8 and tlr9 gene polymorphisms and pulmonary tuberculosis
conclusions tlr8 rs3764880 and tlr9 rs148805533 polymorphisms may not be risk factors for susceptibility to tuberculosis in a sample of iranian population. larger studies are required to validate our findings. results the allelic and genotypic frequencies of the tlr8 rs3764880 did not differ significantly between ptb and the controls. no significant difference was found between the groups regar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Disease Markers
سال: 2011
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2011/545972